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From: Webster's Revised Unabridged Dictionary (1913)

 Con·stringe v. t. [imp. & p. p. Constringed p. pr. & vb. n. Constringing.]  To dawn together; to contract; to force to contract itself; to constrict; to cause to shrink. [R.]
    Strong liquors . . . intoxicate, constringe, harden the fibers, and coagulate the fluids.   --Arbuthnot.