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From: Webster's Revised Unabridged Dictionary (1913)

 Isth·mus n.; pl. Isthmuses   Geog. A neck or narrow slip of land by which two continents are connected, or by which a peninsula is united to the mainland; as, the Isthmus of Panama; the Isthmus of Suez, etc.
 Isthmus of the fauces. Anat. See Fauces.