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From: Webster's Revised Unabridged Dictionary (1913)

 Myx·oe·de·ma n.  Med. A disease producing a peculiar cretinoid appearance of the face, slow speech, and dullness of intellect, and due to failure of the functions of the thyroid gland. [Also spelled myxedema.]-- Myx*oe*dem*a*tous a., Myx*oe*dem*ic a.