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From: Webster's Revised Unabridged Dictionary (1913)

 So·phis·ti·cate v. t. [imp. & p. p. Sophisticated p. pr. & vb. n. Sophisticating.]  To render worthless by admixture; to adulterate; to damage; to pervert; as, to sophisticate wine.
    To sophisticate the understanding.   --Southey.
    Yet Butler professes to stick to plain facts, not to sophisticate, not to refine.   --M. Arnold.
    They purchase but sophisticated ware.   --Dryden.
 Syn: -- To adulterate; debase; corrupt; vitiate.