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From: Webster's Revised Unabridged Dictionary (1913)

 De·range v. t. [imp. & p. p. Deranged p. pr. & vb. n. Deranging.]
 1. To put out of place, order, or rank; to disturb the proper arrangement or order of; to throw into disorder, confusion, or embarrassment; to disorder; to disarrange; as, to derange the plans of a commander, or the affairs of a nation.
 2. To disturb in action or function, as a part or organ, or the whole of a machine or organism.
    A sudden fall deranges some of our internal parts.   --Blair.
 3. To disturb in the orderly or normal action of the intellect; to render insane.
 Syn: -- To disorder; disarrange; displace; unsettle; disturb; confuse; discompose; ruffle; disconcert.