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From: Webster's Revised Unabridged Dictionary (1913)

 Dis·af·fect v. t. [imp. & p. p. Disaffected; p. pr. & vb. n. Disaffecting.]
 1. To alienate or diminish the affection of; to make unfriendly or less friendly; to fill with discontent and unfriendliness.
    They had attempted to disaffect and discontent his majesty's late army.   --Clarendon.
 2. To disturb the functions of; to disorder.
    It disaffects the bowels.   --Hammond.
 3. To lack affection for; to be alienated from, or indisposed toward; to dislike. [Obs.]