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From: Webster's Revised Unabridged Dictionary (1913)

 Rue n.
 1. Bot. A perennial suffrutescent plant (Ruta graveolens), having a strong, heavy odor and a bitter taste; herb of grace. It is used in medicine.
 Then purged with euphrasy and rue
 The visual nerve, for he had much to see.   --Milton.
    They [the exorcists] are to try the devil by holy water, incense, sulphur, rue, which from thence, as we suppose, came to be called herb of grace.   --Jer. Taylor.
 2. Fig.: Bitterness; disappointment; grief; regret.
 Goat's rue. See under Goat.
 Rue anemone, a pretty springtime flower (Thalictrum anemonides) common in the United States.
 Wall rue, a little fern (Asplenium Ruta-muraria) common on walls in Europe.