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From: Webster's Revised Unabridged Dictionary (1913)

 Sof·ten·ing, a. & n. from Soften, v.
 Softening of the brain, or Cerebral softening Med., a localized softening of the brain substance, due to hemorrhage or inflammation. Three varieties, distinguished by their color and representing different stages of the morbid process, are known respectively as red, yellow, and white, softening.