vi·cis·si·tude /vəˈsɪsəˌtud, vaɪ, ˌtjud/
 變化,變遷,榮枯,盛衰
 Vi·cis·si·tude n.
 1. Regular change or succession from one thing to another; alternation; mutual succession; interchange.
 God made two great lights . . .
 To illuminate the earth and rule the day
 In their vicissitude, and rule the night.   --Milton.
 2. Irregular change; revolution; mutation.
    This man had, after many vicissitudes of fortune, sunk at last into abject and hopeless poverty.   --Macaulay.
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 vicissitude
      n 1: a variation in circumstances or fortune at different times
           in your life or in the development of something; "the
           project was subject to the usual vicissitudes of
           exploratory research"
      2: mutability in life or nature (especially successive
         alternation from one condition to another)